The Ultimate Probiotic
The intestines range from a relatively alkaline environment (pH) of
the small intestine to an increasingly acidic environment in the large
intestine. No one strain of bacteria can provide benefits throughout
the entire length of the alimentary canal. This is the reason that Jarrow
Formulas® Jarro-Dophilus EPS® supplies eight different strains.
In the small intestine (duodenum, jejunum, and ileum), the primary
lactic flora which can be supplemented are the lactobacilli, although
enterococci are also present. The large intestine exhibits a large
proportion of bifidobacteria in addition to its components of lactobacilli
and enterococci. The typical intestinal and vaginal flora includes
several different species of lactic acid bacteria which perform different
activities according to the nature of their enzyme systems. In the case
of carbohydrate processing, for example, Lactobacillus rhamnosus
ferments at least 24 different carbohydrates: L. acidophilus, up to
16; and L.delbrueckii subsp. bulgaricus, 7 different carbohydrates.
This means that the lactic bacteria are important for completing
the processing of carbohydrates in the gut. Bifidobacteria, which
are located mainly in the large intestine, can ferment a variety of
undigested carbohydrates, such as lactulose and oligosaccharides,
and produce lactic and acetic acids. This provides the body’s “friendly
bacteria” its best protection against unfriendly bacteria and yeast.*
Probiotic bacteria are important aids to normal digestion and
assimilation beyond the simple processing of carbohydrates.* Some
species of lactic acid bacteria contribute to the digestion of proteins,
some deconjugate bile salts, some produce specific beneficial
bacteriocins, while others enhance the immune response.* The eight
different species found in Jarro-Dophilus EPS are representatives of
four different genera: lactobacillus, bifidobacteria, lactococcus, and
pediococcus.
Jarro-Dophilus EPS helps to safeguard and preserve the health
of the entire intestinal tract with a mixture of the most important
lactobacilli species which include Lactobacillus rhamnosus, L. casei,
L. plantarum, and L. acidophilus.* Bifidobacterium longum BB536
(Morinaga strain) has been shown in well-controlled clinical trials to
stimulate immune response and to promote the growth of beneficial
bacteria.* BB536 also has been shown to reduce the production of
IgE, which is related to a healthy histamine response.* R0052 has been
shown to support normal bowel functioning, as well as to enhance
gastrointestinal health.* Lactobacillus rhamnosus R0011 is a species,
which prolifically produces unique polysaccharides which augment
intestinal immune response and also facilitate probiotic colonization.*
Administration of strains R0052 and R0011 together resulted in more
normal bowel responses in children.* Pediococcus helps to minimize
putrification in the gut and produces novel pediocins (antibiotic-like
bacteriocins).*
Requirements for Multi-Species Probiotic Success
There are several properties that are required from strains of lactic
acid bacteria if these are to result in an efficient probiotic. No single
strain can easily fulfill all these requirements. A mixture of species,
therefore, is usually most suitable for supplementation. The most
desirable properties of a good probiotic are:
• Compatibility among the strains
• Ability to survive passage through the digestive tract
• Stable under normal gastric conditions
• Resistance to bile salts
• Adherence to intestinal mucosa
• Colonization of the human intestinal tract
• Safety with regard to human use
• Production of natural antimicrobial substances*
• Antagonism against unfriendly and putrefactive bacteria*
• Stability during storage under normal conditions
5 Billion Organisms Per Capsule
At the time of manufacture, Jarro-Dophilus EPS supplies 5 billion live
organisms per capsule. Even very hardy species of probiotics must
be supplied in sufficient quantities if they are to properly colonize the
gut and favorably influence bowel health. Newly advanced processing
techniques now permit the production of very concentrated sources
of probiotic bacteria, which have been carefully selected for their
complimentary interaction with one another.
Enteric Coated to Protect Against Stomach Acid
The acidity of the stomach forms an important natural barrier against
the entry of bacteria and yeasts into the rest of the digestive tract.
However, this same barrier can impede probiotic supplementation.
Jarro-Dophilus EPS enteric coated capsules bypass the acid barrier
and thereby optimize the amount of friendly bacteria to the intestines,
giving superior results with fewer capsules.
*These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.
** IMNatural Customer Service Representatives are not licensed health care providers and therefore cannot prescribe or recommend products by law.